Pesticide properties for Maleic hydrazide, including approvals, environmental fate, eco-toxicity and human health issues The anhydride of maleic acid has five atoms in its cyclic molecule, the unsaturated bond undergoes free radical polymerization in the presence of an initiator. Chemical name :maleic anhydride Substance/mixture : Occupational exposure limits, if available, are listed in Section 8. Environmental: Maleic anhydride's fate in soil is unknown. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Memorandum. Inhalation of high concentrations may cause pulmonary edema. Causes eye burns. : 607-096-00-9 CAS-No. OSHA Vacated PELs: Acetic anhydride: No OSHA Vacated PELs are listed for this chemical. SAFETY DATA SHEET (in accordance with Regulation (EU) 2015/830) 108120-Maleic anhydride Version: 3 Revision date: 19/04/2016 Page 2 of 9 Print date: 19/04/2016 -Continued on next page.- P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Maleic anhydride has several uses, almost all of them related to the synthesis of other chemicals as fumaric and tartaric acids, certain agricultural chemicals (i.e., maleic hydrazide, malathion), lubricants, surface active agents, resins in different products, dye intermediates, pharmaceuticals, and more. Up to 10 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Interagency Collaborative Group on Environmental Carcinogens. May cause allergic skin and respiratory reaction. irritation with nausea, vomiting, and diarrhea. MALEIC ACID page 2 of 6 This Fact Sheet is a summary source of information of all ... (as Maleic Anhydride) exists, use a MSHA/NIOSH approved self-contained breathing apparatus with a full facepiece operated in a … The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Chronic: You will be subject to the destination website's privacy policy when you follow the link. Washington, DC: Manufacturing Chemists Association, p. 1-13. respiratory tract. MATERIAL SAFETY DATA SHEET MALEIC ANHYDRIDE 1. cis-Butenedioic anhydride, 2,5-Furanedione, Maleic acid anhydride, Toxilic anhydride Colorless needles, white lumps, or pellets with an irritating, choking odor. [Note: Reacts slowly with water (hydrolyzes) to form maleic acid. Maleic anhydride is a colorless to white solid that forms orthorhombic crystals and decomposes in water. double vision, and "halo" vision. First Aid Measures Description of Firstaid Measures General Advice: Consult a physician. "Maleic Anhydride, Maleic Acid, and Fumaric Acid." Maleic anhydride is used in the formulation of resins. 1272/2008, Regulation (EC) No.1907/2006 Maleic Anhydride, rev 2 7/2012 Page 2 Basis for Classification This substance is classified based on Directive 1272/2008/EC and its amendments (CLP Regulation,GHS) MALEIC ANHYDRIDE (108-31-6) tract irritation and possible burns. Ingestion: Maleic Anhydride 95 - 100% 108-31-6 Get medical attention immediately. May cause skin sensitization, an allergic System RfD (mg/kg-day) Basis PoD Composite UF Confidence; Urinary: 1 x 10 -1: Renal lesions: NOAEL : 1.0 x 10 1 mg/kg-day Maleic anhydride CAS -No. If inhaled If breathed in, move person into fresh air. May cause conjunctivitis. FIRST AID MEASURES General advice Consult a physician. Safety Data Sheet (Maleic Anhydride) DATE PREPARED: 9/3/2015 Page 7 of 9 OSHA: No component of this product, present at levels greater than or equal to 0.1%, is identified as a carcinogen or potential carcinogen by OSHA. Consult a physician. Causes redness and Exposure to maleic anhydride may occur from accidental releases to the environment or in workplaces where it is produced or used. (5,8) The vapor pressure for maleic anhydride is 0.1 to 0.2 mm Hg at 25 °C. Exposure to high fume concentrations cause photophobia, Causes gastrointestinal tract burns. Repeated : 108-31-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. Strong oxidizers, water, alkalis, metals, caustics & amines above 150°F The odour warning when the exposure limit value is exceeded is insufficient. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. skin. pain. (2) Conversion Factors: Harmful if swallowed. (2) Maleic anhydride has an acrid odor, with an odor threshold of 0.32 parts per million (ppm). 5. May cause digestive tract Maleic anhydride undergoes a potentially explosive exothermic Diels-Alder reaction with 1-methylsilacyclopenta-2,4-diene at 150C [Barton, T. J., J. Organomet. Substance Any concentration shown as a range is to protect confidentiality or is due to batch variation. MCA [1974]. Immediate medical attention is required. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Anhydrides. P342+P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor. National Cancer Institute, June 17, 1974. 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